Home | Articles
Tue, 02/10/2015 - 09:04  |  Anonymous
Published on:10th Feb 2015
Indian Journal of Pharmaceutical Education and Research, 2010; 44(3):301-310
Review Article | doi:Nill

Pharmaceutical Impurities: An Overview


Authors and affiliation (s):

N. Rama Rao, S. S. Mani Kiran* and Prasanthi N.L.

Chalapathi Institute of Pharmaceutical Sciences, Lam, Guntur- 522034

Abstract:

The impurities in pharmaceuticals are unwanted chemicals that remain with the active pharmaceutical ingredients (APIs) or develop during formulation or upon aging of both API and formulation. The presence of these unwanted chemicals even in trace amount may influence the efficacy and safety of pharmaceutical product. The control of impurities is currently a critical issue to the pharmaceutical industry. International Conference on Harmonization (ICH) formulated guidelines regarding the control of impurities. This review outlines the description of different types and origins of impurities and degradation routes with specific examples.

Key words: Impurities, formulation, efficacy, degradation.

 




 

Login to post comments  |  Tags:

Impact Factor

IJPER - An Official Publication of Association of Pharmaceutical Teachers of India is pleased to announce continued growth in the Latest Release of Journal Citation Reports (source: Web of Science Data).

 

Impact Factor® as reported in the 2023 Journal Citation Reports® (Clarivate Analytics, 2023): 0.8

The Official Journal of Association of Pharmaceutical Teachers of India (APTI)
(Registered under Registration of Societies Act XXI of 1860 No. 122 of 1966-1967, Lucknow)

Indian Journal of Pharmaceutical Education and Research (IJPER) [ISSN-0019-5464] is the official journal of Association of Pharmaceutical Teachers of India (APTI) and is being published since 1967.

DOI HISTORY

IJPER uses reference linking service using Digital Object Identifiers (DOI) by Crossref. Articles from the year 2013 are being assigned DOIs for its permanent URLs

 

Indian Journal of Pharmaceutical Education and Research is an official Publication of Association of Pharmaceutical Teachers of India, Bangalore. The journals and its contents are licensed under a Creative Commons Attribution-Non Commercial-No Derivs 4.0 License. Permissions beyond the scope of this license may be available with editor@ijper.org

Ind.J Pharm.Edu. Res. [http://www.ijper.org]
[ISSN:0019-5464] EMANUSCRIPT Services