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Wed, 02/11/2015 - 11:09  |  Anonymous
Published on:11th Feb, 2015
Indian Journal of Pharmaceutical Research and Education, 2011; 45(4):324-325
Pharmaceutical Education | doi:Nill

Buzzer-Assisted Plethysmometer for the Measurement of Rat Paw Volume


Authors and affiliation (s):

Kulkarni A.R*, Ganguly K, Kiran Chaturvedi, Karale S and Singh R.M

Department of Pharmacology, S.E.T's College of Pharmacy, Dharwad - 580 002, Karnataka

Abstract:

A sensitive and reproducible method of measuring rat paw volume was developed by connecting electrical buzzer to conventional plethysmometer.This methodology combined ease of operation and precision as the end point is detected by buzzer system. Standard error of mean (SEM) were calculated for the volume measured by both conventional as well as buzzer-assisted plethysmometer and results indicated that calculated values of SEM were 0.02 and 0.037 for buzzer-assisted and conventional plethysmometer respectively. Presently developed buzzer-assisted plethysmometer may be a useful tool for the students carrying out research on inflammation.

Keywords: Plethysmometer, Edema, Inflammatio

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